If youβre working hard at the gym and wondering,Β βDoes vaping affect muscle growth?β, the short answer is yesβit can.Β Vaping may not ruin your muscle gains overnight, but several studies suggest it has the potential to interfere with key processes your body uses to build muscle. Below is a clear, easy-to-understand explanation of how vaping and muscle growth interact, and what it could mean for your training.
How Muscle Growth Works

Muscle growth (hypertrophy) happens when you stress your muscles through resistance training. Your body then repairs and builds them larger by:
- Repairing muscle micro-tears.
- Activating protein synthesis (building new muscle protein).
- Releasing hormones like testosterone and growth hormone.
- Having good blood flow to deliver oxygen and nutrients to muscle tissue.
If any of these steps get disrupted, muscle growth can slow down.
Ways Vaping Might Affect Muscle Growth
Here is how vaping can affect muscle growth:
-
Reduced blood flow and oxygen delivery
Nicotine and other chemicals in vaping can cause blood vessels to constrict (narrow) and reduce how effectively your body delivers oxygen and nutrients to muscles. One study noted that young people who vaped showed lower peak exercise capacity compared to non-vapers. -
Hormonal impacts
Nicotine may raise cortisol (a stress hormone) and lower testosterone, which is important for building muscle. Elevated cortisol over time can lead to more muscle breakdown and less muscle building. -
Reduced protein synthesis and slower recovery
Research shows nicotine might interfere with the processes your body uses to repair muscle and build new muscle fibres. One review noted that nicotine βcan affect how cells make proteins necessary for muscle repair.β -
Decreased endurance and workout quality
If your lungs and cardiovascular system are less efficient (which vaping may contribute to), it can lower your performance during workoutsβmeaning less effective training, fewer reps or sets, and slower progress.
How Strong Are the Effects?
Itβs important to note that the evidence is emerging and not all studies show the same level of impact. Some of the factors that affect how much vaping influences muscle growth include:
- How much and how often you Vape (nicotine strength, frequency).
- Your overall health, fitness level, and training habits.
- How well you handle other aspects of recovery (sleep, nutrition, stress).
- Whether you vape with nicotine or use nicotine-free e-liquids (nicotine appears to be the main driver of these effects).
In short, vaping is less harmful than smoking in many waysβbut βless harmfulβ doesnβt mean βharmless,β especially when you care about muscle growth and fitness.
What This Means for You If Youβre Training
If your goal is to build muscle and optimise your gym gains, here are some practical takeaways:
- Consider reducing or quitting vaping, especially nicotine-rich types, to remove one possible barrier to muscle growth.
- Make sure you optimise other key muscle-building habits: ample protein intake, good sleep, progressive overload in training, and rest days.
- If you still vape, try to stay aware of how it might impact your workout quality, recovery and overall endurance.
- Monitor how you feel during workouts: if youβre getting winded more easily, feeling slower to recover or noticing stalled progress, vaping may be a contributing factor.
- Always consult with healthcare or fitness professionals if you want personalised advice, especially if you have underlying health conditions.
Final Thoughts
In conclusion: vaping can affect muscle growthβnot necessarily in dramatic ways for everyone, but the negative effects on circulation, hormones, recovery and workout performance are credible and backed by emerging research. If muscle growth, strength and fit-body goals are your priority, eliminating or significantly reducing vaping gives you a clearer path to maximised results.